● SYSTEM STATUS: ALL NODES OPERATIONAL   |   PROTOCOL VERSION 4.2.1   |  
Neural mapping resolution increased by 340% — see full report Orpheus Labs receives ISO 27001 certification renewal New collaboration with Geneva Institute of Cognitive Sciences Research grant approved — €14.2M — Project MNEMOSYNE Symposium on Consciousness Digitization — Vienna, March 2025 Neural mapping resolution increased by 340% — see full report Orpheus Labs receives ISO 27001 certification renewal New collaboration with Geneva Institute of Cognitive Sciences Research grant approved — €14.2M — Project MNEMOSYNE Symposium on Consciousness Digitization — Vienna, March 2025
Est. 2009 — Geneva, Switzerland

Mapping the boundaries of human consciousness

We are a private research institute dedicated to understanding, preserving, and ultimately bridging the gap between biological and digital cognition.

312
Published studies
47
Researchers
9
Active programs
// ORPHEUS SYSTEM v4.2.1
// RUNTIME ENVIRONMENT: ACTIVE



Research Focus

Three pillars of inquiry

Our interdisciplinary approach combines neuroscience, computational theory, and bioethics to advance the frontier of consciousness research.

RES-001 / NEURAL MAPPING

High-fidelity Brain Digitization

Developing non-destructive scanning protocols capable of capturing synaptic architecture at nanometer resolution, enabling complete neural map reconstruction.

Active — Phase III
RES-002 / COGNITION

Consciousness Substrate Transfer

Investigating the theoretical and practical frameworks for migrating conscious experience from biological substrates to synthetic computational environments.

Active — Phase II
RES-003 / BIOETHICS

Digital Identity & Continuity

Examining the philosophical, ethical, and legal implications of consciousness preservation — identity, personhood, and the rights of digital entities.

Active — Ongoing
Latest Publications

Peer-reviewed research

Our findings are published across leading journals in neuroscience, cognitive science, and computational biology.

View all publications →
2024 · Nature Neuroscience
Lossless synaptic density encoding via multi-photon tomography
Renaud, V. · Chen, X. · Hoffmann, L. et al.
2024 · Journal of Consciousness Studies
Continuity of Self in Non-Biological Substrates: A Theoretical Model
Elara M. · Hoffmann, L.
2023 · Cell
The MNEMOSYNE Protocol: Encoding episodic memory in synthetic matrices
Chen, X. · Vasari, P. · Renaud, V. et al.
2023 · Frontiers in Bioethics
Personhood and the Digital Mind: legal frameworks for the 21st century
Elara M.
Partners & Affiliations

Trusted by leading institutions

ECOLE POLYTECHNIQUE
FÉDÉRALE
GENEVA INSTITUTE
COGNITIVE SCI.
NEUROTEC
CONSORTIUM
MAX PLANCK
INSTITUTE
EU HORIZON
PROGRAMME